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2 054 005

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IPC

(21) (22)

Application

94008236/04, 1993-03-10

(22)

Actual filing date

1993-03-10

(45)

Published

1996-02-10

(72)

Inventor

Chupakhin O.N.Charushin V.N.Rusinov V.L.Mokrushina G.A.Kotovskaja S.K.Baskakova Z.M.Kolmakova T.V.

(73)

Holder

Nauchno-Tekhnologicheskoe Predprijatie

METHOD FOR PRODUCTION OF 1-ETHYL-6-FLUORO-7-(PIPERAZINYL-1)-4-OXO-1,4-DIHYDRO-3-QUINOLINE CARBOXYLIC ACID Russian patent published in 1996 - IPC

Abstract RU 2054005 C1

FIELD: medicine. SUBSTANCE: desired product 1-ethyl-6-fluoro-7-(piperazinyl-1)-4-oxo-1,4-dihydro-3-quinoline carboxylic acid having formula is prepared by interaction of 1-ethyl-6-fluoro-7-halogen-4-oxo-1,4-dihydro-3-quinoline carboxylic acids or their esters with piperazine hexahydrate. The process is carried out in aqueous solution in the presence of potassium carbonate or triethylamine. EFFECT: improves efficiency of method.

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RU 2 054 005 C1

Authors

Chupakhin O.N.

Charushin V.N.

Rusinov V.L.

Mokrushina G.A.

Kotovskaja S.K.

Baskakova Z.M.

Kolmakova T.V.

Dates

1996-02-10—Published

1993-03-10—Filed