FIELD: chemical industry. SUBSTANCE: malononitrile is affected by nitrosation at 10-15 C within 1.5-2.0 h. The process is carried out in aqueous medium with the help of sodium nitrite, organic or mineral acid being used as catalyst. Quantity of said catalyst is 0.01-0.02 moles per 1 mole of malononitrile. Thus prepared sodium salt of isonitroso malononitrile is added to aqueous solution of guanidine hydrochloride or guanidine nitrate being heated preliminary to 40-50 C. Quantity of said solution is 1.05-1.15 moles. Then cooling and filtration thus obtained guanidine salt are carried out. Said salt is placed in butanol and 0.15-0.25 moles of sodium hydroxide are added. The process is followed by heating at 105-115 C within 0.5-1.0 h, by filtration, washing by water and drying. EFFECT: improves efficiency of method. 3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF SYNTHESIS OF 2,4,6-TRIAMINO-6-PHENYLPTERIDINE | 1993 |
|
RU2047616C1 |
| METHOD OF SYNTHESIS OF 2,4,6-TRIAMINO-5-NITROSOPYRIMIDINE | 1989 |
|
RU1624955C |
| METHOD OF PRODUCING 1,2-BENZISOTHIAZOLIN-3-ONE | 2012 |
|
RU2614424C2 |
| PROCESS FOR PREPARING N-(β-HYDROXYETHYL)-4,6-DIMETHYLDIHYDROPYRIMIDON-2 | 1992 |
|
RU2044730C1 |
| METHOD OF PRODUCING IMATINIB AND INTERMEDIATE COMPOUNDS THEREOF | 2007 |
|
RU2480461C2 |
| METHOD OF OBTAINING SODIUM SALT OF 2-METHYLTHIO-6-NITRO-1,2,4-TRIAZOLO[5,1-c]-1,2,4-TRIAZIN-7-ONE, DIHYDRATE | 2007 |
|
RU2343154C2 |
| METHOD OF PREPARING 1-NITROSO-4-METHYLPIPERAZINE | 1993 |
|
RU2095355C1 |
| METHOD OF PREPARING TRANS-1,4,5,8-TETRANITROSO-1,4,5,8- TETRAAZADECALINE | 1997 |
|
RU2144532C1 |
| METHOD OF TEREPHTHALIC ACID N,@@@-DIPHENACYLAMIDE SYNTHESIS | 0 |
|
SU1747437A1 |
| METHOD OF EXTRACTING SODIUM SULPHATE AND METAL NITRATES | 2015 |
|
RU2610076C1 |
