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2 057 805

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IPC

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Application

94004840/13, 1994-02-08

(22)

Actual filing date

1994-02-08

(45)

Published

1996-04-10

(72)

Inventor

Zhesterev V.I.Balysheva V.I.Churbanova G.N.Vishnjakov I.F.Kurinnov V.V.

(73)

Holder

Vserossijskij Nauchno-Issledovatel'Skij Institut Veterinarnoj Virusologii I Mikrobiologii

STRAIN SWINE FEVER VIRUS FOR PREPARING VACCINE AGAINST CLASSIC SWINE PLAGUE Russian patent published in 1996 - IPC

Abstract RU 2057805 C1

FIELD: microbiology. SUBSTANCE: new strain of classic swine plague virus multiplicating at high infectious activity 5.0-6.5 lgBOE5 0/ml in transplanted cell cultures and showing high thermoresistance as compared with that of the strain ЛК-ВНИИВВиМ and retaining immunogenicity. Strain "ЛК-К" classic swine plague is deposited in Collection of ВНИИВВиМ at N 1842. Strain is obtained by limit dilution cloning method and selection of obtained clones by trait - multiplication at the high titer in transplanted cell cultures. Cloning is carried out by limit dilution method for 5 passages. As a result, the clone is isolated accumulating in transplanted cell cultures at titers 5.5-7.0 lgBOE5 0/ml. Stability of this trait is retained for 50 passages (observation period). Obtained virus clone is designed as "ЛК-К". EFFECT: preparing new strain indicated above. 1 tbl

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RU 2 057 805 C1

Authors

Zhesterev V.I.

Balysheva V.I.

Churbanova G.N.

Vishnjakov I.F.

Kurinnov V.V.

Dates

1996-04-10—Published

1994-02-08—Filed

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