METHOD OF PREPARING INACTIVATED VACCINE AGAINST CLASSIC PLAGUE IN PIGS Russian patent published in 1995 - IPC

Abstract RU 2049477 C1

FIELD: virology. SUBSTANCE: monolayer transplanted cell culture is infected with cultural virulent variant of virus, strain Shi-Myn. Prepared virus-containing material showing activity 105,0-106,5 50 ml is frozen and thawed and inactivated with copper sulfate at final concentration 3-6 mmole/ml virus-containing material. Vaccine is administrated by intramuscularly in neck or thigh region twice at 14 days interval. Vaccine is harmless and shows immunogenicity and absence reaction response. EFFECT: improved method of vaccine preparing. 4 tbl

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RU 2 049 477 C1

Authors

Zhesterev V.I.

Balysheva V.I.

Churbanova G.N.

Ustarov R.D.

Vishnjakov I.F.

Dates

1995-12-10Published

1993-04-23Filed