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(19)

(11)

2 061 695

(13)

(51)

IPC

(21) (22)

Application

93028444/04, 1993-05-28

(22)

Actual filing date

1993-05-28

(45)

Published

1996-06-10

(72)

Inventor

Frehnk R. Bush[Us]Pol' Bouls[Us]Duglas Dzh. M. Allen[Us]Sabeto A. Diroma[Us]Dennis M. Godek[Us]

(73)

Holder

Pfajzer Ink.

METHOD FOR PRODUCTION OF ARYL PIPERAZINE HETEROCYCLIC COMPOUNDS OR THEIR PHARMACEUTICALLY ACCEPTABLE ACID ADDITIVE SALT Russian patent published in 1996 - IPC

Abstract RU 2061695 C1

FIELD: organic chemistry. SUBSTANCE: piperazine having formulae (2) is used as reagent 1, alkyl halide-containing compound having formula (3) is used as reagent 3. Reaction is carried out by heating to boiling point, reaction takes place in water in the presence of sodium carbonate, its quantity being 1-4 molar equivalents as calculated for origin reagent. Desired product which has formula (1) is prepared at yield 88-91 %. Said product has neuroleptic activity. EFFECT: improves quality of desired product.

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RU 2 061 695 C1

Authors

Frehnk R. Bush[Us]

Pol' Bouls[Us]

Duglas Dzh. M. Allen[Us]

Sabeto A. Diroma[Us]

Dennis M. Godek[Us]

Dates

1996-06-10—Published

1993-05-28—Filed