THERAPEUTIC PEPTIDES OR THEIR PHARMACEUTICALLY ACCEPTABLE SALTS Russian patent published in 1997 - IPC

Abstract RU 2088592 C1

FIELD: chemistry of proteins, amino acids. SUBSTANCE: product: peptides of the general formula (I): R1R12

-Ao- A1-Trp-A4 - A5 -A6 - A7-W where: Ao - Gly, D-Ala, D-Phe, D-p-Nal or without the latter; A1 - p-Glu, Asn, D-Ala, D-Phe, D-Leu, D-Trp, D-p-Nal or D-p-halide-Phe or without the latter; A2 - p-Glu, Gln, Leu, His; A4 - Ala; A5 - Val, Phe, Thr; A6 - Sar, Gly, D-Ala; A7 - His; W - fragment NHCHZ; R3 - COV or NHCHZ; R4CHZ2COV or NR12R13, or their pharmaceutically acceptable salts showing bombesine activity. EFFECT: improved method of synthesis. 19 cl, 3 dwg

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RU 2 088 592 C1

Authors

Dehvid Kh.Koj[Us]

Zhak-P'Er Moro[Us]

Dzhon E.Tejlor[Us]

Sun Kh'Juk Kim[Us]

Dates

1997-08-27Published

1989-10-13Filed