A STABILIZING COMPOSITION TO OBTAIN LYOPHILIZED PREPARATIONS BASED UPON CONJUGATE OF IMMUNOGLOBULIN G AND HORSE RADISH PEROXIDASE Russian patent published in 1998 - IPC

FIELD: biotechnology, immunology, immunobiology. SUBSTANCE: the given stabilizing composition contains protein hydrolysate, saccharose, phosphate-saline buffer, bacteriostatic, bovine serum albumin, EDTA (trilon B) and potassium chloride at the following ratio of components, weight%: bovine serum albumin 0.1-3.0; saccharose 1.0-10.0; protein hydrolysate 1.0-5.0; potassium chloride 2.0-8.0; EDTA (trilon B) 0.03-0.2; bacteriostatic 0.01-0.02; phosphate-saline buffer - the rest. Peptone and gelatin are used as protein hydrolysate and merthiolate is applied as bacteriostatic. Stabilizer provides the safety of biochemical properties of anti-IgG conjugate preparation and horse radish peroxidase during lyophilic drying, subsequent storage and rehydration at the room temperature. EFFECT: higher efficiency to obtain stable types of immunobiological preparations which keep their specific properties for a long period of time. 2 cl, 3 tbl