STRAIN OF HYBRID CULTURED CELL OF ANIMAL RATTUS NORVEGICUS USED FOR PREPARING MONOCLONAL ANTIBODIES RAISED TO HUMAN HEPATITIS A VIRUS Russian patent published in 1999 - IPC

Abstract RU 2142507 C1

FIELD: biotechnology, immunology. SUBSTANCE: strain of hybrid transplanted cells IBM 612 is obtained by the fusion of rat myeloma cells 210RC. Y3-Ag1.2.3 with splenocytes LOU from rats immunized with the purified preparation of hepatitis A virus. The strain of hybrid transplanted cells IBM 612 produces monoclonal antibodies IgG2B that interact specifically with hepatitis A virus. Monoclonal antibodies are used as reagents in diagnostic test-systems for detection of hepatitis A virus antigens and antibodies. EFFECT: strain indicated above, specific antibodies preparing. 1 tbl, 3 ex

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RU 2 142 507 C1

Authors

Kazachinskaja E.I.

Loktev V.B.

Razumov I.A.

Dates

1999-12-10Published

1997-05-13Filed