FIELD: biotechnology, immunology. SUBSTANCE: strain of hybrid transplanted cells IBM 612 is obtained by the fusion of rat myeloma cells 210RC. Y3-Ag1.2.3 with splenocytes LOU from rats immunized with the purified preparation of hepatitis A virus. The strain of hybrid transplanted cells IBM 612 produces monoclonal antibodies IgG2B that interact specifically with hepatitis A virus. Monoclonal antibodies are used as reagents in diagnostic test-systems for detection of hepatitis A virus antigens and antibodies. EFFECT: strain indicated above, specific antibodies preparing. 1 tbl, 3 ex
Title |
Year |
Author |
Number |
STRAIN OF HYBRID CULTURED CELLS OF ANIMAL MUS MUSCULUS L FOR PREPARING MONOCLONAL ANTIBODIES RAISED TO PROTEIN 105 KDA OF EXCRETORY-SECRETORY ANTIGEN OF HUMAN HEPATIC TREMATODE OPISTHORCHIS FELINEUS |
1997 |
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2004 |
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- Loktev Valerij Borisovich
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2008 |
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2004 |
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|
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2015 |
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|
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2008 |
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|
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2008 |
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2008 |
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- Sorokin Aleksandr Vladimirovich
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2000 |
- Nikolenko G.N.
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2008 |
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