HOLLOW MICROCAPSULES, METHOD FOR PREPARING DIAGNOSTIC MEANS CONTAINING HOLLOW MICROCAPSULES AND METHOD FOR APPLYING THEM TO SET DIAGNOSIS Russian patent published in 1998 - IPC

FIELD: medicine. SUBSTANCE: method involves spraying solution in heated gas medium or dispersing material suitable for building microcapsule walls in liquid carrier. Then the carrier is evaporated. Solution or dispersed material are used in concentration of 0.1-50 % by mass/volume. The microcapsules are delivered for applying spray method for drying under pressure of (11-10) 10⁵ Pa. Gas is heated to 100-250 C at the spray drying chamber entrance and to 40-150 C at the exit from it. The so produced microcapsules allow additional processing to reduce their solubility in water at least from the outside of the capsules by heating or irradiating or chemically binding. Protein like collagen or gelatin or serum albumin are usable as the material suitable for building microcapsule walls. EFFECT: wide range of applications for visualization and ultrasonic diagnosis. 16 cl, 3 dwg , 2 tbl