METHOD FOR PRODUCING PENICILLIN MICROCAPSULES IN KAPPA-CARAGEENAN Russian patent published in 2015 - IPC A61K9/50 A61K31/43 A61K47/30 A61J3/07 

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to microencapsulation, particularly to a method for producing penicillin microcapsules. According to the method, a microcapsule coating is kappa-carageenan; a weighed amount of kappa-carageenan in acetone is added with a drug powder in the presence of the surfactant E472c; the drug to kappa-carageenan ratio at a dry basis makes from 1:1 to 1:3; after an independent solid phase is formed, carbinol 5 ml and distilled water 1 ml are added very slowly drop by drop; the prepared suspension of the microcapsules is filtered, washed and dried; the encapsulation process takes 15 minutes.

EFFECT: method provides simplifying and accelerating the penicillin microencapsulation in kappa-carageenan.

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