METHOD OF PREPARING THE BONE-MARROW INHIBITOR OF THE STEM HEMOPOIETIC CELL PROLIFERATION Russian patent published in 1998 - IPC

Abstract RU 2110268 C1

FIELD: medicine, hematology. SUBSTANCE: method involves preparing bone-marrow cells, preliminary heating the isolated cell extract at 40-80 C for 10-60 min, its cooling and centrifugation at the rate 3000-6000 rev. /min. Dissolved precipitate is subjected for chromatography on column with reversed-phase sorbent in system of trifluoroacetic acid at acetonitrile gradient. EFFECT: increased yield, specific activity and homogeneity of the end product.

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RU 2 110 268 C1

Authors

Kozlov V.A.

Orlovskaja I.A.

Akimenko Z.A.

Tsyrlova I.G.

Dates

1998-05-10—Published

1994-11-15—Filed