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2 110 276

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C1

(51)

IPC

(21) (22)

Application

5067684/14, 1992-10-05

(22)

Actual filing date

1992-10-05

(45)

Published

1998-05-10

(72)

Inventor

Frank G.A.Pugachev K.K.Shimbireva I.B.Belous T.A.

(73)

Holder

Moskovskij Nauchno-Issledovatel'Skij Onkologicheskij Institut Im.P.A.Gertsena

METHOD OF PREPARING BETA-2-GLOBULIN FROM HUMAN FETUS MECONIUM Russian patent published in 1998 - IPC

Abstract RU 2110276 C1

FIELD: immunology, immunochemistry, oncology. SUBSTANCE: invention relates to preparing antigen used for animal immunization. For this purpose human fetus meconium extract is used in mixture with specific antiserum to beta-2-MA. Formed suspension precipitate is washed out from additional components and beta-2-MA is isolated by dissociation of immune complex in acid medium, pH 2.2-2.0. Invention can be used for development of industrial technology for production of immunochemical test-systems for beta-2-MA assay in histology for diagnosis of primary and metastatic neoplasmas. EFFECT: increased yield, improved method of preparing. 1 dwg, 1 tbl

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RU 2 110 276 C1

Authors

Frank G.A.

Pugachev K.K.

Shimbireva I.B.

Belous T.A.

Dates

1998-05-10—Published

1992-10-05—Filed

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