FIELD: biotechnological industry, antibiotics. SUBSTANCE: strain of Streptomyces cremeus 1979 GNZA 2166 - a producer of antibiotic apramycin is obtained by mutagen effect on museum culture Streptomyces cremeus subsp. tobramycini followed by step variants selection showing maximal productivity with respect to apromycin accumulation and the absence of concomitant antibiotics. EFFECT: strain indicated above, increased production of apramycin.
| Title | Year | Author | Number |
|---|---|---|---|
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| STRAIN OF ASPERGILLUS FRESENIUS 4238 - A PRODUCER OF FUMAGILLIN | 1995 |
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| STRAIN STREPTOMYCES CREMEUS SUBSPECIES NEBRAMYCINI FBM-0002 - PRODUCER OF APRAMYCIN | 1996 |
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| METHOD FOR PREPARATION OF INOCULUM MATERIAL - A PRODUCER OF AMINOGLYCOSIDE ANTIBIOTIC COMPLEX OF STREPTOMYCES CREMEUS SUBSP "NEBRAMYCINI" | 0 |
|
SU1735366A1 |
| INOCULUM NUTRIENT MEDIUM FOR PREPARATION OF AMINOGLYCOSIDE ANTIBIOTIC COMPLEX | 0 |
|
SU1735367A1 |
| ENZYMATIC NUTRIENT MEDIUM FOR PREPARATION OF AMINOGLYCOSIDE ANTIBIOTIC COMPLEX | 0 |
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| METHOD FOR PREPARATION OF AMINOGLYCOSIDE ANTIBIOTIC COMPLEX | 0 |
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| STRAIN STREPTOMYCES FRADIAE - A PRODUCER OF TYLOSIN | 1994 |
|
RU2065878C1 |
