AMINOACETIC ACID DERIVATIVES AS RACEMATES OR D-AND L- ENANTIOMERS OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, METHOD OF PREPARING D-AND L-ENANTIOMERS OF AMINOACETIC ACID DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF, AND AMINOACETIC ACID D-AND L-ENANTIOMERS AS CINCHONIDINE SALTS Russian patent published in 1998 - IPC

FIELD: medicine. SUBSTANCE: D-and L-enantiomers of D-amino-10, 11-dihydro-5H-dibenzo [a,d] cyclohepten -5-acetic acid derivatives are prepared by reacting racemate with (-) cinchonidine in solvent, the resulting product is separated by fractionation crystallization to form D-and L-enantiomers. The resulting novel compounds are useful for preparing biologically active peptides which are essentially endoteline antagonist used for treating hypertension, myocardial infarction, metabolic, endocrinological and neurological disorders. EFFECT: improved properties of the title compounds. 12 cl