FIELD: organic chemistry, antibiotics. SUBSTANCE: product: derivatives of cephalosporin of the general formula (I): $$$ where R means hydrogen atom, $$$-alkyl or $$$-haloidalkyl; A and $$$ taken together mean group of the formulas (II) $$$, (III) $$$, (IV) $$$ and (V) $$$ where Y means nitrogen or hydrogen atom and X means hydrogen, halogen atom, $$$-alkyl, $$$-alkoxyl, amino- or nitro-group, or their pharmaceutically acceptable salts. Pharmaceutical composition has cephalosporin derivative of the general formula (I) as an active component and pharmaceutically acceptable carrier. EFFECT: improved method of synthesis. 9 cl, 1 tbl
Authors
Dates
1998-02-10—Published
1992-01-03—Filed