FIELD: microbiology, biotechnology. SUBSTANCE: invention proposes mutant strain 1-365 of Antarctic black yeast Nadsoniella nigra var. hesuelica as a producer of melanin-containing biologically active addition. Indicated strain produces the broad spectrum of biological macrobiotic activity. Antiradical effect of addition stops degradative effect of labile free radicals. Addition is used for foodstuffs, medicinal and cosmetic agents. Addition is toxicless and exhibits as small-dispersed black crystalline powder of flicking luster or its an aqueous solution. EFFECT: yeast strain indicated above, enhanced effectiveness of an agent. 4 cl, 6 ex
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