FIELD: medicine, virology. SUBSTANCE: vaccination against viral hepatitis B is carried out for two stages with vaccine containing hepatitis B virus antigen obtained by culturing the transformed cells of the strain S. cerevisiae VKPM-Y-2203. The second administration of vaccine is carried out mainly in 4-5 months after the first one. By emergency indications the second administration is carried out in 2-3 months after the first one. Invention can be used in medicine for prophylaxis and propagation of viral hepatitis B. EFFECT: high frequency of seroconversions, significant level of immunity. 3 cl, 1 tbl
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Authors
Dates
1998-07-27—Published
1997-08-19—Filed