FIELD: cardiovascular surgery. SUBSTANCE: native tissue from freshly slaughtered animals is treated with mixture of epoxy compounds at temperature from 4 to 45 C for 2 to 21 days and then with solution of heparin with concentration 75 unit/ml at 20-45 C for 2 to 16 hr, after which tissue is ethylated with 70% aqueous ethanol. EFFECT: increased tromb resistance of tissue and suppressed calcification. 4 cl, 1 tbl, 2 ex
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