FIELD: medicine.
SUBSTANCE: invention concerns medicine, particularly cardiovascular surgery, and can be applied in sterilisation and storage of bioprostheses. Method of sterilisation and pre-implantation storage of biological prostheses for cardiovascular surgery involves flushing of preliminarily preserved biological prosthesis in sterile 0.9% sodium chloride solution and prosthesis placement in sterilisation agent on phosphate buffer. 2-bromine-2-nitropropane-1.3-diol bactericide medication obtained with 0.05-0.2 M phosphate buffer at pH 4.0-8.0 in 0.01-2.0% concentration at 5-40°C is used as sterilisation agent.
EFFECT: high antibacterial activity, preserved resilience of biomaterial and structure of biological tissue, significant reduction of bioprosthesis flushing time before implantation.
3 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| BIOCIDAL COMPOSITION FOR ASEPTIC STORAGE OF PRESERVED PROSTHETIC MATERIAL FROM TISSUES OF ANIMAL ORIGIN | 2014 |
|
RU2580621C1 |
| METHOD OF PRE-IMPLANT STORAGE OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY | 2016 |
|
RU2633062C1 |
| METHOD OF ANTICALCIUM TREATMENT OF BIOLOGICAL PROSTHESES OF HEART VALVES | 2008 |
|
RU2374843C1 |
| METHOD OF PRESERVATION AND STERILISATION OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY | 2007 |
|
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| METHOD FOR STERILISATION AND PRE-IMPLANTATION STORAGE OF BIOLOGICAL PROSTHESES OF XENOGENIC AND ALLOGENIC TISSUE FOR CARDIOVASCULAR SURGERY | 2011 |
|
RU2457867C1 |
| METHOD FOR PRE-IMPLANTATION PREPARATION OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY | 2014 |
|
RU2558089C1 |
| METHOD FOR MAKING BIOLOGICAL VENOUS-VALVE PROSTHESIS | 2010 |
|
RU2429023C1 |
| METHOD FOR TREATING BIOMATERIALS FOR CARDIOVASCULAR SURGERY | 2001 |
|
RU2196424C1 |
| METHOD FOR MANUFACTURE OF VALVE-CONTAINING CONDUIT FROM CATTLE JUGULAR VEIN | 2016 |
|
RU2633544C1 |
| METHOD FOR MANUFACTURING CARCASSLESS BIOLOGICAL PROSTHESIS OF CARDIAC AORTIC VALVE | 2001 |
|
RU2211685C2 |
