FIELD: medicine.
SUBSTANCE: what is described is a method for making a biological venous-valve prosthesis comprising valve-containing segments of bovine vein preserved in 2-5 % ethylene glycol diglycidyl ether at temperature 18-30°C for 21 days; a biomaterial is then gradually modified by layers in heparin solution 100 Unit/ml for 16 hours, then in human albumin solution 3-20 g/l at pH 3.5-6.0 for 3 hours and over again in heparin solution for 4 hours. Before use, the biological prosthesis is stored in 2 % ethylene glycol diglycidyl ether.
EFFECT: improved hemocompatibility of the biological prosthesis ensured by modification of the valve-containing segments of bovine vein preserved in ethylene glycol diglycidyl ether.
1 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD FOR MANUFACTURE OF VALVE-CONTAINING CONDUIT FROM CATTLE JUGULAR VEIN | 2016 |
|
RU2633544C1 |
| METHOD FOR PRE-IMPLANTATION PREPARATION OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY | 2014 |
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| METHOD OF ANTICALCIUM TREATMENT OF BIOLOGICAL PROSTHESES OF HEART VALVES | 2008 |
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| METHOD FOR CONSERVATION OF BIOLOGICAL TISSUES FOR PROSTHETICS OF HEART AND VESSEL VALVES | 1992 |
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| BIOCIDAL COMPOSITION FOR ASEPTIC STORAGE OF PRESERVED PROSTHETIC MATERIAL FROM TISSUES OF ANIMAL ORIGIN | 2014 |
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| METHOD OF STERILISATION AND PRE-IMPLANTATION STORAGE OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY | 2007 |
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| METHOD OF PRODUCTION OF PENTAGLYCIDYL ETHER OF GLUCOSE AND COMPOSITION BASED ON IT FOR CHEMICAL LINKING OF COLLAGEN-CONTAINING ENDOPROSTHESES OF BIOLOGICAL ORIGIN | 2014 |
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| METHOD OF PRE-IMPLANT STORAGE OF BIOLOGICAL PROSTHESES FOR CARDIOVASCULAR SURGERY | 2016 |
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