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2 124 502

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IPC

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Application

93053674/04, 1993-11-23

(22)

Actual filing date

1993-11-23

(45)

Published

1999-01-10

(72)

Inventor

Smirnov L.D.Kesarev O.G.Gatsura V.V.Sernov L.N.Ragimov A.A.Rozonov Ju.B.Burov Ju.V.

(73)

Holder

Aktsionernoe Obshchestvo Zakrytogo Tipa

β-HYDROXY ETHYLAMINIUM NICOTINATE DERIVATIVES HAVING ANTIISCHENIC ACTIVITY Russian patent published in 1999 - IPC

Abstract RU 2124502 C1

FIELD: medicine. SUBSTANCE: novel chemical compounds, more particularly β- hydroethylaminium-5- hydroxynicotinates of formula I: β wherein R is CH₂CH₂OH(XC-1), CH₃(XC-2), H(XC-3), said compounds have antiischemic activity. Desired compounds are prepared by reacting 5- hydroxynicotinic acid with corresponding aminoalkyls in the presence of solvent during heating operation. In experiments on animals, said compounds show high antiischemic activity and low toxicity. EFFECT: improved properties of the title compounds. 2 ex, 4 tbl

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RU 2 124 502 C1

Authors

Smirnov L.D.

Kesarev O.G.

Gatsura V.V.

Sernov L.N.

Ragimov A.A.

Rozonov Ju.B.

Burov Ju.V.

Dates

1999-01-10—Published

1993-11-23—Filed