GAMMA-HYDROXYPROPYLAMMONIUM-5-HYDROXYNICOTINATE ELICITING ANTI-ISCHEMIC, ANTI-ARRHYTHMIC AND HYPOLIPIDEMIC ACTIVITY Russian patent published in 2005 - IPC

Abstract RU 2245329 C1

FIELD: organic chemistry, chemical technology, medicine.

SUBSTANCE: invention relates to synthesis of new biologically active substance, namely, to γ-hydroxypropylammonium-5-hydroxynicotinate of the formula (I): , eliciting an anti-ischemic, anti-arrhythmic and hypolipidemic activity. This compound shows low toxicity and absence of cardiodepressive effect. Compound of the formula (I) is prepared by interaction of 5-hydroxynicotinic acid with 3-amino-1-propanol in the presence of a solvent at heating.

EFFECT: valuable medicinal properties of compound.

1 cl, 7 tbl, 3 ex

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RU 2 245 329 C1

Authors

Sernov L.N.

Smirnov L.D.

Kesarev O.G.

Shaposhnikova G.I.

Dates

2005-01-27Published

2003-09-10Filed