USE OF 2-PHENYL-3-ARAYLBENZOTHIOPHENES FOR THROMBOMODULINE EXPRESSION ENHANCEMENT Russian patent published in 1999 - IPC

Abstract RU 2125450 C1

FIELD: organic chemistry. SUBSTANCE: invention proposes a new agent of the formula (I): where R1 and R3 mean independently hydrogen, CH3, where Ar means optionally substituted phenyl; R2 is taken from a group consisting of pyrrolidino-, hexamethyleneimino- or piperidino-group, or its pharmaceutically acceptable salts or solvates. Synthesized compounds enhance an expression of thrombomoduline by inhibition thrombotic disorder. EFFECT: improved method of synthesis, enhanced effectiveness of compounds, broadened pattern of agents. 4 cl

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RU 2 125 450 C1

Authors

Dehvid Skott Kehlnek

Brian Vill'Jam Grinnell

Dates

1999-01-27Published

1994-12-19Filed