DERIVATIVE OF HUMAN C-PROTEIN AND A PHARMACEUTICAL COMPOSITION SHOWING ANTITHROMBIC EFFECT Russian patent published in 1998 - IPC

Abstract RU 2122004 C1

FIELD: medicine, genetic engineering. SUBSTANCE: aspartic acid at position 167 in human natural C-protein is replaced with phenylalanine, aspartic acid at position 172 is replaced with asparagine residue and asparagine residue at position 313 is replaced with glutamine residue. Derivative of human C-protein is used at effective amount as an active component with acceptable solvent or carrier for pharmaceutical composition preparing. EFFECT: enhanced effectiveness of C-protein activation. 3 cl, 5 ex, 6 tbl

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RU 2 122 004 C1

Authors

Brjus Ehdvard Gerlitz

Brajen Uil'Jam Grinnell

Dates

1998-11-20—Published

1993-05-19—Filed