DRY METHOD FOR PREPARING PARTICLES BASED ON ACTIVE PRINCIPLES, DRY PARTICLES PREPARED BY THIS METHOD, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH PARTICLES Russian patent published in 1999 - IPC

Abstract RU 2125869 C1

FIELD: pharmaceutical industry. SUBSTANCE: invention relates to dry preparation of essentially spherical particles consisting of high-activity substance introduced into biologically compatible polymer with high boiling temperature, this polymer and above-mentioned high-activity substance being admixed under stirring to immiscible homogeneous viscous carrier. Stirring is continued until formation of biologically compatible polymer microbeads and complete introduction of high-activity substance into them are attained. Temperature of this process is not higher than vitrification temperature of polymer. EFFECT: enabled formation of microbeads with load on core material more than 15% and which have no high-activity substance on their surfaces. 16 cl, 10 ex

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RU 2 125 869 C1

Authors

Rjuiz Zhan-Mark

Dates

1999-02-10Published

1994-05-13Filed