DUAL INHIBITORS OF NO-SYNTHASE AND CYCLOOXYGENASE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION BASED ON THEREOF Russian patent published in 1998 - IPC

Abstract RU 2104999 C1

FIELD: organic chemistry, biochemistry. SUBSTANCE: invention relates to compounds of the general formula (AB) which can be salts or amides and where A means inhibitor of cyclooxygenase having available acid functional group; B means L-form of arginine analogs of the formula: where R1,R2 and R3 are different substituents. Invention relates to a method of synthesis of these compounds and their pharmaceutical compositions. EFFECT: improved method of synthesis, enhanced effectiveness of compositions. 8 cl, 8 tbl

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RU 2 104 999 C1

Authors

P'Er-Eht'Enn Shabrie De Lasson'Er[Fr]

P'Er Brake[Fr]

Kolett Broke[Fr]

Serzh Oven[Fr]

Dates

1998-02-20Published

1992-12-31Filed