FIELD: pharmaceutical means. SUBSTANCE: invention relates to sterile dosed stable composition of crystalline amiphostine and pharmaceutically acceptable carrier. Crystalline amiphostine S-2-(3-aminopropylamino)ethyl dehydrophosphothioate is prepared by mixing crude amiphostine with alcohol and water to form solution containing no undissolved particles at temperature from about 20 to 10 C. Solution is cooled below 0 C to precipitate crystalline product. Resultant composition is free of undissolved particles. EFFECT: increased stability of composition. 31 cl, 13 dwg, 9 ex
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