FIELD: chemistry.
SUBSTANCE: invention relates to salts and crystalline forms of (S)-6-chloro-7-(1,1-dimethylethyl)-2-trifluoromethyl-2H-1-benzopyran-3-carboxylic acid, wherein the salt is selected from the group consisting of a potassium salt and a meglumine salt, as well as a pharmaceutical composition based on said compounds for the treatment of diseases mediated by a cyclooxygenase-2 inhibitor, a method for preparation and use thereof.
EFFECT: said compounds show good formulation properties such as high aqueous solubility, good intrinsic dissolution, good crystallinity, good thermal stability or low hygroscopicity.
11 cl, 10 dwg, 1 tbl, 12 ex
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