ANNEALED DIHYDROPYRIDINE DERIVATIVES OR SALTS THEREOF WITH PHYSIOLOGICALLY TOLERABLE ACIDS AND AGENT BLOCKING NONSELECTIVE CATIONIC PASSAGES Russian patent published in 1999 - IPC

FIELD: chemical industry. SUBSTANCE: invention describes ANNEALED dihydropyridine derivatives of general formula (I) wherein A is benzo- or thieno group; R² is hydroxyl, alkoxyl, benzyloxy, halogen, alkyl; m is 0, if A is thieno group and 2, if A is benzo group; R¹ is C_4-6 cycloalkyl or group of formula II: wherein R⁵ is alkyl, azido group, halogen, alkoxyl, n is 1, 2 or 3, n is 0, if A is thieno group; R³ and R⁴ are hydrogen, C_3-6 alkenyl, C_3-6 alkynyl, C_1-12 alkyl which is substituted with thienyl or phenyl, or R³ is hydrogen, R⁴ is cyclohexyl, phenyl, fluorophenyl, pyridyl or benzylpiperidyl; or R³ and R⁴ together with nitrogen atom form pyrrolidinyl, piperidinyl, group of formula III: or piperazinyl unsubstituted or substituted by group of formula IV: , or salts thereof with physiologically tolerable acids. The invention describes agent blocking nonselective cationic passages wherein active agent is compound of formula (I) or salt thereof with physiologically tolerable acid. EFFECT: improved properties of compounds and agent. 3 cl, 15 tbl, 6 ex