STABILIZED ERYTHROPOIETIN AQUEOUS SOLUTION Russian patent published in 1999 - IPC

Abstract RU 2128517 C1

FIELD: medicine, pharmacy. SUBSTANCE: invention proposes aqueous solution containing erythropoietin at concentration 500-4000 IU/1 ml, dextran of molecular mass 30000-60000 Da at concentration 6-10 wt.-%, sodium citrate and citric acid to obtain isotonicity and pH value of solution 6.5-7.5. Solution can contain additionally 5 wt.-% of mannitol or glucose. Invention provides to get useful life of solution up to 2 years under storage conditions at 2-8 C. Obtained stable erythropoietin solution can be used for treatment of patients with anemia. EFFECT: enhanced efficiency. 3 cl, 2 dwg, 1 tbl, 5 ex

Similar patents RU2128517C1

Title	Year	Author	Number
PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF NEUROLOGIC DISEASES	2007	Dudkin Sergej Marovich Kurochkin Sergej Nikolaevich Kolobkov Sergej Leonidovich Volchek Igor' Anatol'Evich Lukachevskij Pavel L'Vovich	RU2335296C1
IMMUNOMODELLING PREPARATION FOR INJECTION-FREE APPLICATION	2001	Volchek I.A. Dudkin S.M. Kurochkin S.N. Kolobkov S.L. Morozova E.N. Kozlov V.A.	RU2197986C2
METHOD FOR ERYTHROPOIETIN PREPARATION	0	Peteshev Vitalij Mikhajlovich Gudim Valentina Ivanovna Ivanova Valentina Sergeevna Sochnev Vasilij Vasilevich Kim Radij Egorovich Smirnova Lyudmila Viktorovna	SU1651909A1
TABLET FORM OF RECOMBINANT HUMAN ERYTHROPOIETIN	2000	Sandakhchiev L.S. Kolokol'Tsova T.D. Varaksin N.A. Kostina N.E. Jurchenko N.D. Shumakova O.V. Nechaeva E.A. Rjabicheva T.G. Belova N.V. Kolokol'Tsova O.A.	RU2182830C1
TEST SYSTEM FOR DIAGNOSTICS OF AGENTS OF ACUTE RESPIRATORY VIRAL INFECTIONS	2019	Klotchenko Sergei Anatolevich Vasin Andrei Vladimirovich Plotnikova Marina Aleksandrovna Taraskin Aleksandr Sergeevich Lozhkov Aleksei Aleksandrovich Giulikhandanova Nataliia Evgenevna Elpaeva Ekaterina Sergeevna Griadunov Dmitrii Aleksandrovich Filippova Marina Aleksandrovna Savvateeva Elena Nikolaevna	RU2733379C1
STRAIN OF CULTIVABLE HYBRID MUS MUSCULUS CELLS FOR PRODUCING MONOCLONAL ANTIBODIES TO HUMAN INTERLEUKIN	0	Ovchinnikov Yurij Anatolevich Lunev Vitalij Evgenevich Nesmeyanov Vladimir Andreevich Kazennykh Natalya Vladimirovna Belyaev Sergej Vasilevich	SU1472498A1
METHOD OF RECOMBINANT PROTEIN LIQUID MEDICINAL FORM PREPARING	2001	Beljakov N.V. Korobitsyn L.P. Pivovarov A.M. Prokop'Ev A.A.	RU2180233C1
SET FOR QUANTITATIVE DETERMINATION OF AVERMECTINS VIA SINGLE-STEP COMPETITIVE ENZYME-IMMUNOASSAY	2009	Tarasov Il'Ja Evgen'Evich Tsibezov Valerij Vladimirovich Nepoklonov Anatolij Aleksandrovich Aliper Taras Ivanovich Verkhovskij Oleg Anatol'Evich	RU2416094C1
METHOD FOR IMMUNOFLUORESCENT DETECTION OF PROTECTIVE ANTIGEN OF ANTHRAX AGENT	2011	Belova Elena Valentinovna Luneva Nina Mikhajlovna Kolesnikov Aleksandr Vladimirovich Kozyr' Arina Vladimirovna Shemjakin Igor' Georgievich Djatlov Ivan Alekseevich	RU2478970C1
STRAIN OF CULTIVABLE HYBRID MUS MUSCULUS CELLS FOR PRODUCING MONOCLONAL ANTIBODIES TO HUMAN INTERLEUKIN	0	Ovchinnikov Yurij Anatolevich Lunev Vitalij Evgenevich Nesmeyanov Vladimir Andreevich Kazennykh Natalya Vladimirovna Belyaev Sergej Vasilevich Tsimanis Aleksandr Yurevich Onoprienko Lyudmila Viktorovna Mikhaleva Inessa Ivanovna	SU1472499A1

RU 2 128 517 C1

Authors

Dates

1999-04-10—Published

1998-07-20—Filed