FIELD: medicine, pharmacology. SUBSTANCE: invention proposes an agent for inhibition of neurotoxicity caused by β--amyloid peptides. This agent is a compound of the general formula (I) early known as an antiestrogen: 
where R1 and R2 mean independently each of other hydrogen atom, -CH3, 
-alkyl) or 
-Ar where Ar is optionally substituted phenyl; R2 is taken from a group consisting of pyrrolidine- and piperidine-group, or its pharmaceutically acceptable salt or solvate. EFFECT: broadened pattern of an agents for indicated prescription. 2 cl, 3 ex
