INHIBITION OF SMOOTH MUSCLE CELLS PROLIFERATION AND RESTENOSIS Russian patent published in 2000 - IPC

FIELD: organic chemistry, medicine. SUBSTANCE: invention relates to the novel agent used for inhibition of proliferation of aorta smooth muscle cells or for inhibition of artery restenosis caused by proliferation of smooth muscle cells. This proposed agent is the known substances of the formula (I) or (II) where R¹ and R³ mean independently hydrogen atom, -CH₃, -alkyl) or -Ar where Ar is optionally substituted phenyl; R² is taken among the group including pyrrolidino- and piperidino-group; R⁴ means hydrogen atom or OR¹, and its pharmaceutically acceptable salt. EFFECT: broadened arsenal of agents. 8 cl, 8 comp, 1 dwg