FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of 5-amino-8-methyl-7- -pyrrolidinylquinoline-3-carboxylic acid of the formula (I) 
where R1 - H; R2 - H, lower alkyl, halogenated lower alkanoyl or a carboxylic acid ester residue; R3-R6 - hydrogen atom or lower alkyl or two of R4,R5,R6 can form in common a group -(CH2)n where n = 2, their stereoisomers or their pharmacologically acceptable salts which show an excellent antibacterial activity. EFFECT: improved method of synthesis, strong antibacterial activity. 17 cl, 7 tbl, 37 ex
| Title |
Year |
Author |
Number |
| METHOD OF PRODUCING DERIVATIVE OF QUINOLINE OR ITS PHARMACEUTICALLY ACCEPTABLE ESTER, OR THEIR SALTS |
0 |
- Yun-Iti Matsumoto
- Teruyuki Miyamoto
- Khirosi Egava
- Siniti Nakamura
|
SU1588281A3 |
| METHOD OF PRODUCING DERIVATIVE QUINOLINE OR ITS PHARMACEUTICALLY ACCEPTABLE ESTER, OR THEIR DERIVATIVES |
0 |
- Yun-Iti Matsumoto
- Teruyuki Miyamoto
- Khirosi Egava
- Siniti Nakamura
|
SU1582986A3 |
| DEHALOGENATED COMPOUNDS, ANTIBACTERIAL AGENT AND THERAPEUTIC AGENT BASED ON THEREOF, METHOD FOR PREPARING ANTIBACTERIAL OR MEDICINAL AGENT, USING DEHALOGENATED COMPOUNDS FOR PREPARING ANTIBACTERIAL OR MEDICINAL AGENT |
2001 |
- Takakhasi Khisasi
- Mijauti Rie
- Itokh Masao
- Takemura Makoto
- Khajakava Isao
|
RU2298006C2 |
| SPIROCOMPOUND OR SALTS THEREOF, METHOD OF PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION BASED THEREON HAVING ANTIMICROBIAL ACTIVITY |
1989 |
- Isao Khajakava[Jp]
- Sokhgo Atarasi Masazumi Jmamura[Jp]
- Euiti Kimura[Jp]
|
RU2094432C1 |
| METHOD OF PRODUCING DERIVATIVE OF QUINOLINE OR ITS PHARMACEUTICALLY ACCEPTABLE ESTER, OR THEIR SALTS |
0 |
- Yun-Iti Matsumoto
- Teruyuki Miyamoto
- Khirosi Egava
- Siniti Nakamura
|
SU1588282A3 |
| METHOD OF PRODUCING QUINOLINE DERIVATIVES, THEIR ESTERS OR SALTS USED IN PHARMACY |
0 |
- Yun-Iti Matsumoto
- Teruyuki Miyamoto
- Khirosi Egava
- Siniti Nakamura
|
SU1627086A3 |
|
0 |
- Dzun-Iti Matsumoto
- Akira Minamida
- Masakhiro Fudzita
- Tokhru Khirose
- Dzundzi Nakano
- Siniti Nakamura
|
SU1780533A3 |
| METHOD OF SYNTHESIS OF 8-CHLOROQUINOLONE DERIVATIVE |
1991 |
- Jusuke Jukimoto[Jp]
- Tokhru Kanejuti[Jp]
- Ioiti Kimura[Jp]
- Katsukhiro Kavakamis[Jp]
- Isao Khajjakava[Jp]
|
RU2049778C1 |
| PROCESS FOR PREPARING QUINOLINE DERIVATIVES OR PHARMACEUTICALLY ACCEPTABLE ESTERS THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS OF THESE DERIVATIVES OR ESTERS |
0 |
- Yun-Ichi Matsumoto
- Teruyuki Miyamoto
- Khirosi Egava
- Sinichi Nakamura
|
SU1635898A3 |
| CYCLOALKYL-SUBSTITUTED DERIVATIVES OF AMINOMETHYLPYRROLIDINE AND ANTIBACTERIAL AGENT BASED ON THEREOF |
1999 |
- Takemura Makoto
- Takakhasi Khisasi
- Mijauti Rie
- Takeda Tosijuki
- Khajakava Isao
|
RU2248970C2 |
