CYCLOALKYL-SUBSTITUTED DERIVATIVES OF AMINOMETHYLPYRROLIDINE AND ANTIBACTERIAL AGENT BASED ON THEREOF Russian patent published in 2005 - IPC

FIELD: organic chemistry.

SUBSTANCE: invention relates to new antibacterial agents. Invention describes cycloalkyl-substituted derivatives of aminomethylpyrrolidine represented by the general formula (I): wherein each among R¹ and R² represents hydrogen atom; n represents a whole number from 1 to 4; Q represents structural moiety represented by the following formula (Ia): wherein R³ represents cyclic alkyl group comprising from 3 to 6 carbon atoms that can be substituted; R⁴ represents hydrogen atom; R⁵ represents hydrogen atom or amino-group; X¹ represents halogen or hydrogen atom; A¹ represents nitrogen atom or structural moiety represented by the formula (II): wherein X² represents hydrogen, halogen atom or alkyl group comprising from 1 to 6 carbon atoms, or alkoxyl group comprising from 1 to 6 carbon atoms; X² and R³ can form a ring structure in common with part of the parent skeleton optionally comprising oxygen, nitrogen or sulfur atom as a ring-forming atoms and optionally comprising alkyl group comprising from 1 to 6 carbon atoms as a substitute; Y represents hydrogen atom. Also, invention describes an antibacterial an agent containing compound by cl. 1. Invention provides preparing new compounds eliciting valuable biological properties.

EFFECT: valuable properties of compounds and agent.

15 cl, 1 tbl, 10 ex