FIELD: chemical industry. SUBSTANCE: acetyl decarboxamide oxytetracycline impurity is removed from oxytetracycline. Oxytetracycline containing acetyldecarboxamide oxytetracycline impurity is suspended in glacial acetic acid, mixture is stirred for 5 hours, the resulting precipitate of tetracycline hydrochloride acetate is filtered, washed with acetic acid and acetone and then dried at reduced pressure and temperature not higher than 40 C till constant weight is attained, and transformed into oxytetracycline base. EFFECT: improved purification of the desired product. 5 cl, 6 ex
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