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IPC

(21) (22)

Application

95112132/04, 1995-07-12

(22)

Actual filing date

1995-07-12

(45)

Published

1999-07-20

(72)

Inventor

Seredenin S.B.(Ru)Blednov Ju.A.(Ru)Andronati Sergej AndreevichPavlovskij Viktor IvanovichJavorskij Aleksandr Stepanovich

(73)

Holder

Nauchno-Issledovatel'Skij Institut Farmakologii RamnFiziko-Khimicheskij Institut Im.A.V.Bogatskogo Natsional'Noj Akademii Nauk Ukrainy

1,4-BENZODIAZEPINE DERIVATIVES SHOWING SELECTIVE ANXIOLYTIC ACTIVITY Russian patent published in 1999 - IPC

Abstract RU 2133248 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to the novel derivatives of 1,4-benzodiazepine of the general formula (I) where R¹ is bromine atom; R² is CH₃O, NH, NH₂; R³ - H, halogen atom showing the selective anxiolytic activity and with activating component mainly. The above indicated compounds show the expressed anxiolytic effect at the broad range of doses without by-side sedative and myorelaxant effects. Compounds show low toxicity and can be used in psychiatry practice, for prophylaxis of emotion-stress disorders as daily tranquilizers. EFFECT: anxiolytic effect of compounds. 3 dwg, 13 tbl, 4 ex

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RU 2 133 248 C1

Authors

Seredenin S.B.(Ru)

Blednov Ju.A.(Ru)

Andronati Sergej Andreevich

Pavlovskij Viktor Ivanovich

Javorskij Aleksandr Stepanovich

Dates

1999-07-20—Published

1995-07-12—Filed