FIELD: medicine, neuroimmunology. SUBSTANCE: invention relates to test for antigens associated with cerebrospinal sclerosis. Also, invention relates to generation of hybridomas which produce monoclonal antibodies showing specificity to antigens associated with cerebrospinal sclerosis and to polypeptide also. Invention can be used for diagnosis of cerebrospinal sclerosis, in current clinic observation of patients with cerebrospinal sclerosis in relation to disease development or response to therapy. Invention ensures a possibility for diagnosis and treatment of patients with cerebrospinal sclerosis and other myelinizing diseases. EFFECT: improved method of diagnosis and treatment. 22 cl, 3 tbl, 5 dwg, 13 ex
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