METHOD OF DIAGNOSING MALIGNANT TUMORS UTILIZING COMMON TUMOR ANTIGEN-SPECIFIC ANTISERUM Russian patent published in 1999 - IPC

Abstract RU 2137136 C1

FIELD: oncology. SUBSTANCE: embryo in Letus stage is isolated from genetically alike rats and cell suspension is prepared. From immunized animals, spleen cells are taken off to isolate lymphocytes and prepare lymphocyte suspension. Animal of the same genetic line is subjected to second immunization step with above lymphocyte suspension. Thereafter, antiserum is obtained, supplemented by cells of intact organs of the same animals and mixture is decanted. Supernatant is filtered through millipore filter with pore diameter 20 mcm. Filtrate is added to test animal blood for measuring immunofluorescence and erythrocyte sedimentation rate. When measured values are reliably differ from control values, tumor ids diagnosed. EFFECT: increased sensitivity and specificity of diagnostics. 2 cl

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RU 2 137 136 C1

Authors

Erkhov V.S.

Dates

1999-09-10Published

1998-02-27Filed