FIELD: organic chemistry. SUBSTANCE: invention relates to a new compound of the general formula (I) and its pharmaceutically acceptable salts and a method of synthesis of these derivatives and a pharmaceutical composition showing an antiviral activity and containing these derivatives as an active component where R1,R2 and R3 mean independently hydrogen, halogen atom, C1-C5-alkyl; Z means oxygen, sulfur atom and carbonyl group; X means oxygen atom; n = 1-2 and (sub)cycloalk(en)yl means: or where means or where R4 and R5 mean independently hydrogen atom, hydroxymethyl, hydroxymethyl protected by the substituted silyl-group. EFFECT: new nucleoside derivatives, antiviral activity, improved method of synthesis. 4 cl, 1 tbl, 55 ex
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Authors
Dates
1999-09-27—Published
1996-12-30—Filed