NEW ANTIVIRAL HOMOCARBOCYCLIC NUCLEOSIDE DERIVATIVES OF SUBSTITUTED PYRIMIDINEDIONES, METHOD OF THEIR SYNTHESIS AND COMPOSITION CONTAINING THEREOF AS ACTIVE COMPONENTS Russian patent published in 1999 - IPC

Abstract RU 2138487 C1

FIELD: organic chemistry. SUBSTANCE: invention relates to a new compound of the general formula (I) and its pharmaceutically acceptable salts and a method of synthesis of these derivatives and a pharmaceutical composition showing an antiviral activity and containing these derivatives as an active component where R1,R2 and R3 mean independently hydrogen, halogen atom, C1-C5-alkyl; Z means oxygen, sulfur atom and carbonyl group; X means oxygen atom; n = 1-2 and (sub)cycloalk(en)yl means: or where means or where R4 and R5 mean independently hydrogen atom, hydroxymethyl, hydroxymethyl protected by the substituted silyl-group. EFFECT: new nucleoside derivatives, antiviral activity, improved method of synthesis. 4 cl, 1 tbl, 55 ex

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RU 2 138 487 C1

Authors

Euj-Khvan Cho

Sun-Gan Chung

Dzung-Jung Kim

Kho-Seok Kvon

Sun-Khvan Li

Dzae-Eung Li

Dzeong-Kho Dzo

Biung-Chul Kim

Dong-Vuk Kang

Dates

1999-09-27Published

1996-12-30Filed