FIELD: medicine, more precisely, rheumatology. SUBSTANCE: persons under examination are administered to take antipyrine peroraly on empty stomach. Then, content of antipyrine in salive of patient is determined. In case of increase of period of its half-withdrawal and reduced clearance, aggravation of severity of course of rherumatoid arthritis is diagnosed. EFFECT: higher accuracy of prognosis of course of rheumatoid arthritis.
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