FIELD: medicine.
SUBSTANCE: patient's synovial fluid is sampled, and patient's supernatant chemokines CXCL9/MIG, CXCL10/IP-10 and CXCL11/ITAC are measured. A diagnosis of rheumatoid arthritis is diagnosed, if at least one of chemokines exceeds a threshold; the chemokine thresholds make 2625.8 pg/ml for CXCL9/MIG, 3108.2 pg/ml for CXCL9/MIG and 32.4 pg/ml for CXCL11/ITAC respectively. If the measured values are below the thresholds for three chemokines at the same time, the absence of rheumatoid arthritis and potential osteoarthrosis are stated.
EFFECT: using the given method enables differentiating rheumatoid arthritis and osteoarthrosis by measuring specific markers in the synovial fluid taken from the location directly.
2 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHOD OF DIFFERENTIATING HEPATIC FIBROSIS IN CHRONIC VIRAL HEPATITIS B AND AUTOIMMUNE LIVER INJURIES | 2018 |
|
RU2701723C1 |
| METHOD FOR LABORATORY DIAGNOSIS OF STAGES OF HEPATIC FIBROSIS IN CHRONIC VIRAL HEPATITIS C | 2015 |
|
RU2583939C1 |
| METHOD OF DIFFERENTIATION OF BRAIN CONCUSSION, AND MILD, MODERATE AND SEVERE BRAIN CONTUSION | 2023 |
|
RU2798182C1 |
| DIAGNOSTIC TECHNIQUE FOR TUBERCULOSIS INFECTION | 2012 |
|
RU2503006C1 |
| DIAGNOSTIC TECHNIQUE FOR PULMONARY TUBERCULOSIS | 2012 |
|
RU2503005C1 |
| METHOD FOR DIFFERENTIATING CAUSES OF DEVELOPMENT OF INITIAL STAGE OF HEPATIC FIBROSIS IN CHRONIC VIRAL HEPATITIDES B AND C | 2019 |
|
RU2759672C2 |
| KIT FOR DETECTING Q FEVER AGENT IN BIOLOGICAL MATERIAL BY REAL TIME POLYMERASE CHAIN REACTION (RT PCR) | 2012 |
|
RU2525059C2 |
| METHOD FOR PREDICTING THE EFFECTIVENESS OF METHOTREXATE THERAPY IN PATIENTS WITH RHEUMATOID ARTHRITIS | 2020 |
|
RU2753793C1 |
| LYOPHILISED NUTRIENT MEDIUM FOR VISUAL DETECTION OF MYCOPLASMA HOMINIS | 2014 |
|
RU2553549C1 |
| LYOPHILISED NUTRIENT MEDIUM FOR VISUAL IDENTIFICATION OF Ureaplasma urealyticum | 2014 |
|
RU2568062C1 |
