FIELD: biochemistry. SUBSTANCE: described are new substituted 3-acylamino-5-phenyl-1,4- benzodiazepin-2-one of general formula I: 
wherein RI,RII,X1-X4 are as defined in claim 1 which have affinity to cholecystoquinine receptors and are therefore new agonists of cholecystoquinine receptors in yeast of pancreatic amylase. Also described are method of preparation thereof, and intermediate product. EFFECT: more efficient preparation method. 10 cl, 11 ex
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