FIELD: organic chemistry, pharmacy. SUBSTANCE: invention relates to derivatives of 4-phenylaminothiazole of the formula (I) 
where R1, R2 - halogen atom, C1-5-alkyl, C1-5-alkoxyl, trifluoromethyl; R3 - H; R4 is C1-5-alkyl; R5 is C1-5-alkyl, cycloalkyl; n = 0 or 1; R6 is C1-5-alkyl, alkoxyalkyl, cycloalkyl; Z - naphthyl or hetero-aromatic or benzo-condensed group containing 1 or 2 nitrogen atoms as heteroatom possibly substituted with 1-2 substituents taken among halogen atom, alkyl, alkoxyl, alkoxycarbonylalkyl, carboxyalkyl, morpholinocarbonyl, alkylcarbonyl, dialkylamino-carbonylalkyl or alkoxyalkoxyl-group. Their stereoisomers or salts show antagonistic activity with respect to corticotropin-releasing factor. EFFECT: improved method of synthesis, valuable pharmacological properties. 12 cl, 4 tbl, 62 ex
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