FIELD: pharmaceutical industry. SUBSTANCE: invention proposes suppositories containing glycerol, magnesium basic carbonate and Tween-80 and also solid fat of type A or Massupol-15 as a base for suppositories. Suppository has the following composition (for adult), g: glycerol, 1.1-1.6; magnesium basic carbonate, 0.045-0.055; Tween-80, 0.013-0.015; solid fat of type A or Massupol-15 up to, 2.66-2.94 and suppository has the following composition (for children), g: glycerol, 0.55-0.76; magnesium basic carbonate, 0.245-0.255; Tween-80, 0.006-0.008; solid fat of type A or Massupol-15, up to 1.33-1.47. Method involves the use of welded two-layer film consisting of polyvinyl chloride layer and internal polyethylene layer as the package material. Suppositories can be used in constipations of the different etiology. EFFECT: increased stability of suppository, simplified technology of making. 3 cl, 1 tbl, 6 ex
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Authors
Dates
1999-12-27—Published
1999-03-24—Filed