ALCOHOL NITRATES CONTAINING AMIDE, DINITROMETHYLENE AND NITROAMINE GROUPS, METHOD OF PREPARING THEREOF 3- (ACYLAMINODINITROALKYL)TETRAHYDO-1,3-OXAZOLES AND OXAZINES, AND METHOD OF PREPARING THEREOF Russian patent published in 2000 - IPC

Abstract RU 2146243 C1

FIELD: medicine, more particular preparation of cardiovascular medicinals. SUBSTANCE: described are new alcohol nitrates of general formula I: R′C(O)N(R″)(CH2)nC(NO2)2CH2N(NO2)(CH2)mONO2 (1) wherein R′,R″, n and m are as defined in claims, and method of preparing thereof by reaction of nitration of 3- acylaminodinitroalkyl)tetrahydro-1,3-oxazoles and oxazines. Also described are new intermediate compounds, e.g. 3-(acylaminodinitroalkyl)-tetrahydro-1,3-oxazoles and oxazines of general formula II: wherein R′,R″, n and m are as defined in claims, and method of preparing thereof. EFFECT: more efficient preparation method. 8 cl, 6 ex, 2 tbl

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RU 2 146 243 C1

Authors

Korepin A.G.

Galkin P.V.

Perepelkina E.K.

Glushakova N.M.

Eremenko L.T.

Eremenko I.L.

Dates

2000-03-10Published

1998-04-22Filed