FIELD: pharmaceutical industry. SUBSTANCE: invention relates to medicinal form of omeprazol and method of its making. Omeprazol-containing pellets are prepared using sucrose-containing internal core. Indicated core is covered with micronized active substance mixed with mannitol, lactose, sodium lauryl sulfate and sodium hydrogen phosphate that makes solid layer of preparation in applying. Then povidon-containing protective cover is applied. For making the final intestine-soluble cover hydroxypropylmethylcellulose phthalate, cetyl alcohol, acetone and isopropyl alcohol are applied. EFFECT: increased stability of omeprazol in medicinal form. 9 cl, 4 ex
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