TRICYCLIC DERIVATIVES, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION, AND METHOD OF INHIBITION OF VASOPRESSINE Russian patent published in 2000 - IPC

Abstract RU 2149160 C1

FIELD: medicine. SUBSTANCE: described are tricyclic benzazepine derivatives of general formula I: wherein Y,A,B,Z, R1, R2 are as defined in claims and method of preparing said derivatives, pharmaceutical composition based thereon, and method of inhibition of vasopressin. Invention is useful in treating states when it is desirable to reduce vasopressin levels such as cardial insufficiency, or the like. EFFECT: improved properties of the title compounds, and more efficient method of inhibition of vasopressin. 15 cl, 576 ex, 5 tbl

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RU 2 149 160 C1

Authors

Dzhej D. Olbrajt

Mehrvin F. Rejch

Fuk-Vakh Sam

Ksjumej Du

Dates

2000-05-20Published

1994-07-28Filed