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2 163 129

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(51)

IPC

(21) (22)

Application

2000116823/14, 2000-06-29

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Start date

2000-06-29

(22)

Actual filing date

2000-06-29

(45)

Published

2001-02-20

(72)

Inventor

Khavinson V.Kh.Morozov V.G.Semenova V.I.Chajka O.V.Ryzhak G.A.

(73)

Holder

Obshchestvo S Ogranichennoj Otvetstvennost'Ju Instituta Bioreguljatsii I Gerontologii"

METHOD OF PREPARING ANIMAL-ORIGIN COMPLEX OF BIOLOGICALLY-ACTIVE POLYPEPTIDES EXHIBITING ANTIOXIDANT AND GEROPROTECTION ACTIVITIES, PHARMACOLOGICAL AGENT, AND METHOD FOR UTILIZATION THEREOF Russian patent published in 2001 - IPC

Abstract RU 2163129 C1

FIELD: pharmacology. SUBSTANCE: invention, in particular, relates to polypeptide complex isolated from animal pineal gland. For that, gland is homogenized and extracted with acetic acid at 7-15 C in presence of zinc chloride, supernatant is treated with organic solvent, precipitate filtered, washed with acetone, and dried. Resulting intermediate is used to prepare solution with 15-35 mg/ml of peptides. Water-soluble fractions are removed by ultrafiltration to give desired product containing complex of polypeptides with molecular weight ranging from 1000 to 12000 Da. This product is used for preparing pharmacological agent containing above polypeptide complex as active principle. Invention also provides method for preventing and treating age-specific pathology. EFFECT: increased assortment of epyphisial-origin drugs. 6 cl, 6 tbl, 6 ex

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RU 2 163 129 C1

Authors

Khavinson V.Kh.

Morozov V.G.

Semenova V.I.

Chajka O.V.

Ryzhak G.A.

Dates

2001-02-20—Published

2000-06-29—Filed