TETRAPEPTIDE STIMULATING FUNCTIONAL ACTIVITY OF NEURONS, PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD OF ITS USE Russian patent published in 2000 - IPC

Abstract RU 2155063 C1

FIELD: medicine, peptides. SUBSTANCE: invention proposes biologically active compound, tetrapeptide L-alanyl-L-glutamyl-L-asparagyl-L-proline of the general formula: L-Ala-L-Glu-L-Asp-L-Pro, that stimulates functional activity of neurons and pharmacological agent containing effective amount of tetrapeptide of the formula L-alanyl-L-glutamyl-L-asparagyl-L-proline (L-Ala-L-Glu-L-Asp-L-Pro) or its salts as an active component designated for parenteral, intranasal and oral use. Method of stimulation of functional activity of neurons involves prophylactic and/or curative administration to patient pharmacological agent in doses 0.01-100 mcg/kg body mass at least once in a day for time that is necessary to obtain therapeutic effect. Invention can be used as agent stimulating functional activity of neurons in traumas and diseases of nervous system. EFFECT: stimulated functional activity of neurons, normalized metabolism and growth of impaired structures of nervous tissue. 10 cl, 6 tbl, 11 ex

Similar patents RU2155063C1

Title Year Author Number
METHOD OF PREPARING PEPTIDES SHOWING TISSUE-SPECIFIC ACTIVITY AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF 2000
  • Khavinson V.Kh.
RU2161501C1
TETRAPEPTIDE SHOWING GEROPROTECTIVE ACTIVITY, PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD OF ITS USE 1999
  • Khavinson V.Kh.
RU2157233C1
TETRAPEPTIDE STIMULATING FUNCTIONAL ACTIVITY OF HEPATOCYTES, PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD OF ITS USE 2000
  • Khavinson V.Kh.
RU2166957C1
TETRAPEPTIDE REGULATING PROSTATE FUNCTION, PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD OF ITS USING 2001
  • Khavinson V.Kh.
  • Malinin V.V.
  • Grigor'Ev E.I.
RU2177802C1
PEPTIDE COMPOUND RECOVERING FUNCTION OF RESPIRATORY ORGANS 2004
  • Khavinson V.Kh.
  • Grigor'Ev E.I.
  • Ryzhak G.A.
  • Rjadnova I.Ju.
RU2255757C1
PEPTIDE COMPOUND RECOVERING FUNCTION OF MYOCARDIUM 2004
  • Khavinson V.Kh.
  • Ryzhak G.A.
  • Grigor'Ev E.I.
  • Rjadnova I.Ju.
RU2255756C1
AGENT STIMULATING REPARATIVE PROCESSES AND METHOD OF ITS USE 1998
  • Khavinson V.Kh.
  • Morozov V.G.
  • Malinin V.V.
  • Seryj S.V.
RU2139085C1
TETRAPEPTIDE REGULATING GLUCOSE LEVEL IN DIABETES MELLITUS, PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD FOR ITS APPLYING 2003
  • Khavinson V.Kh.
  • Malinin V.V.
  • Grigor'Ev E.I.
  • Ryzhak G.A.
RU2242241C1
AGENT INHIBITING ANGIOGENESIS IN VISUAL ORGAN DISEASE 2001
  • Khavinson V.Kh.
  • Khokkanen V.M.
  • Trofimova S.V.
  • Malinin V.V.
RU2177801C1
TETRAPEPTIDE STIMULATING EYE RETINA FUNCTION, PHARMACOLOGICAL AGENT BASED ON THEREOF AND METHOD OF ITS USING 2000
  • Khavinson V.Kh.
RU2161982C1

RU 2 155 063 C1

Authors

Khavinson V.Kh.

Morozov V.G.

Malinin V.V.

Grigor'Ev E.I.

Dates

2000-08-27Published

1999-10-20Filed