FIELD: organic chemistry, pharmacy. SUBSTANCE: invention describes novel substituted thophensulfonylureas of the general formula (I) 
where R(1) means hydrogen atom or alkyl with one or two carbon atoms; R(2) means hydrogen atom or alkyl with one or two carbon atoms; Y and Z are similar or different and mean halogen atom or alkoxy-group with one or two carbon atoms; X means oxygen or sulfur atom, or their physiologically acceptable salts. Compounds show effect on cardiovascular system. Invention describes method of their synthesis and medicinal agent also. EFFECT: new compounds indicated above, improved method of synthesis, valuable medicinal properties. 6 cl, 7 ex
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